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Medical exposure to ionising radiation and the risk of brain tumours: Interphone study group, Germany

2007; Elsevier BV; Volume: 43; Issue: 13 Linguagem: Inglês

10.1016/j.ejca.2007.06.020

1879-0852

Maria Blettner, Brigitte Schlehofer, Florence Samkange‐Zeeb, Gabriele Berg‐Beckhoff, Klaus Schlaefer, Joachim Schüz,

Advanced Radiotherapy Techniques

Background The role of exposure to low doses of ionising radiation in the aetiology of brain tumours has yet to be clarified. The objective of this study was to investigate the association between medically or occupationally related exposure to ionising radiation and brain tumours. Methods We used self-reported medical and occupational data collected during the German part of a multinational case–control study on mobile phone use and the risk of brain tumours (Interphone study) for the analyses. Results For any exposure to medical ionising radiation we found odds ratios (ORs) of 0.63 (95% confidence interval (CI) = 0.48–0.83), 1.08 (95% CI = 0.80–1.45) and 0.97 (95% CI = 0.54–1.75) for glioma, meningioma and acoustic neuroma, respectively. Elevated ORs were found for meningioma (OR 2.32, 95% CI: 0.90–5.96) and acoustic neuroma (OR 6.45, 95% CI: 0.62–67.16) for radiotherapy to the head and neck regions. Conclusion We did not find any significant increased risk of brain tumours for exposure to medical ionising radiation.