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Selective Delivery of Sex Steroid Hormones to Tissues In Vivo by Albumin and by Sex Hormone‐Binding Globulina

1988; Wiley; Volume: 538; Issue: 1 Linguagem: Inglês

10.1111/j.1749-6632.1988.tb48863.x

1749-6632

William M. Pardridge,

Effects and risks of endocrine disrupting chemicals

Annals of the New York Academy of SciencesVolume 538, Issue 1 p. 173-192 Selective Delivery of Sex Steroid Hormones to Tissues In Vivo by Albumin and by Sex Hormone-Binding Globulina WILLIAM M. PARDRIDGE, WILLIAM M. PARDRIDGE Department of Medicine Division of Endocrinology University of California, Los Angeles, School of Medicine Los Angeles, California 90024Search for more papers by this author WILLIAM M. PARDRIDGE, WILLIAM M. PARDRIDGE Department of Medicine Division of Endocrinology University of California, Los Angeles, School of Medicine Los Angeles, California 90024Search for more papers by this author First published: September 1988 https://doi.org/10.1111/j.1749-6632.1988.tb48863.xCitations: 37 a Supported by National Institutes of Health Grant ROl-DK-25744. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1 Westphal, U. 1971. Steroid-Protein Interactions. Springer-Verlag. New York , NY . 2 Siiteri, P. K. 1981. Extraglandular oestrogen formation and serum binding of oestradial: Relationship to cancer. J. Endocrinol. 89: 119P–129P. 3 Pardridge, W. M. & E. Landaw. 1985. Testosterone transport in brain: Primary role of plasma protein-bound hormone. Am. J. Physiol. 249: E534–E542. 4 Pardridge, W. M. 1987. Plasma protein-mediated transport of steroid and thyroid hormones. Am. J. Physiol. 252: E157–E164. 5 Pardridge, W. M. 1981. Transport of protein-bound steroid hormones into tissues in vivo. Endocr. Rev. 2: 103–123. 6 Pardridge, W. M. & L. J. Mietus. 1979. Transport of steroid hormones through the rat blood-brain barrier. Primary role of albumin-bound hormone. J. Clin. Invest. 64: 145–154. 7 Pardridge, W. M. & E. M. Landaw. 1984. Tracer kinetic model of blood-brain barrier transport of plasma protein-bound ligands. Empiric testing of the free hormone hypothesis. J. Clin. Invest. 74: 745–752. 8 Baird, D. T., H. C. Longcope & J. F. Tait. 1969. Steroid dynamics under steady state conditions. Recent Prog. Horm. Res. 25: 611–664. 9 Vermeulen, A. 1977. Transport and distribution of androgens at different ages. In Androgens and Antiandrogens. L. Martinin & M. Motta, Eds. 53–65. Raven Press. New York , NY . 10 Siiteri, P. K., J. T. Murai, G. L. Hammond, J. A. Nisker, J. W. Raymoure & R. W. Kuhn. 1982. The serum transport of steroid hormones. Recent Prog. Horm. Res. 38: 457–503. 11 Bartlett, P. A. & C. K. Marlowe. 1987. Evaluation of intrinsic binding energy from a hydrogen bonding group in an enzyme inhibitor. Science 235: 569–571. 12 Brown, M. R. 1977. Serum albumin: Amino acid sequence. In Albumin Structure, Function, and Uses. V. M. Rosenoer, M. Oratz & M. A. Rothschild, Eds. 27–51. Pergamon Press. New York , NY . 13 Kragh-Hansen, U. 1981. Molecular aspects of ligand binding to serum albumin. Pharmacol. Rev. 33: 17–53. 14 Terasaki, T. & W. M. Pardridge. 1987. Stereospecificity of triiodothyronine transport into brain, liver, and salivary gland: Role of carrier- and plasma protein-mediated transport. Endocrinology 121: 1185–1191. 15 Weisiger, R., J. Golland & R. Ockner. 1981. Receptor for albumin on the liver cell surface may mediate uptake of fatty acids and other albumin-bound substances. Science Wash. D.C. 211: 1048–1051. 16 Forker, E. L. & B. A. Luxon. 1983. Albumin-mediated transport of rose bengal by perfused rat liver. Kinetics of the reaction at the cell surface. J. Clin. Invest. 72: 1764–1771. 17 Stollman, T. R., R. U. Gartner, L. Theilman, N. Ohmi & A. W. Wolkoff. 1983. Hepatic bilirubin uptake in the isolated perfused rat liver is not facilitated by albumin binding. J. Clin. Invest. 72: 718–723. 18 Stremmel, B. J., B. J. Potter & P. D. Berk. 1983. Studies of albumin binding to rat liver plasma membranes. Implications for the albumin receptor hypothesis. Biochim. Biophys. Acta 756: 20–27. 19 Pardridge, W. M., J. Eisenberg & W. T. Cefalu. 1985. Absence of albumin receptor on brain capillaries in vivo or in vitro. Am. J. Physiol. 249: E264–E267. 20 Pardridge, W. M. 1986. Receptor-mediated transport through the blood-brain barrier. Endocr. Rev. 7: 314–330. 21 Turner, M. R., G. Clough & C. C. Michel. 1983. The effects of cationized ferritin and native ferritin upon the filtration coefficient of single frog capillaries. Evidence that proteins in the endothelial cell coat influence permeability. Microvasc. Res. 25: 205–222. 22 Schneeberger, E. E. & M. Hamelin. 1984. Interaction of serum proteins with lung glycocalyx: its effect on endothelial permeability. Am. J. Physiol. 247 (Heart Circ. Physiol. 10): H206–H217. 23 Mizuma, T., T. Horie, M. Hayashi & S. Awazu. 1986. Albumin-mediated mechanism of drug by isolated hepatocytes. J. Pharmacobio-Dyn. 9: 244–248. 24 Ponder, B. A. J. & M. M. Wilkinson. 1983. Organ-related differences in binding of dolichos biflorous agglutinin to vascular endothelium. Devel. Biol. 96: 535–544. 25 Pardridge, W. M., R. Sakiyama & G. Fierer. 1983. Transport of propranolol and lidocaine through the rat blood-brain barrier. Primary role of globulin-bound drug. J. Clin. Invest. 71: 900–908. 26 Pardridge, W. M., L. J. Mietus, A. M. Frumar, B. Davidson & H. L. Judd. 1980. Effects of human serum on the transport of testosterone and estradiol into rat brain. Am. J. Physiol. 239: E103–E108. 27 Verheugen, C., W. M. Pardridge, H. L. Judd & G. Chaudhuri. 1984. Differential permeability of uterine and liver vascular beds to estrogens and estrogen conjugates. J. Clin. Endocrinol. Metab. 59: 1128–1132. 28 Cefalu, W. T., W. M. Pardridge, G. Chaudhuri & H. L. Judd. 1986. Serum bioavailability and tissue metabolism of testosterone and estradiol in rat salivary gland. J. Clin. Endocrinol. Metab. 63: 20–28. 29 Cefalu, W. T. & W. M. Pardridge. 1987. Augmented transport and metabolism of sex steroids in lymphoid neoplasia in the rat. Endocrinology 120: 1000–1009. 30 Sakiyama, R., W. M. Pardridge & N. A. Musto. 1988. Influx of TeBG and TeBG-bound sex steroid hormones into rat testis and prostate. J. Clin. Endocrinol. Metab. 67: 98–103. 31 Pardridge, W. M., E. M. Landaw, L. P. Miller, L. D. Braun & W. H. Oldendorf. 1985. Carotid artery injection technique: bounds for bolus mixing by plasma and by brain. J. Cereb. Blood Flow Metab. 5: 576–583. 32 Goussis, O., W. M. Pardridge & H. L. Judd. 1983. Critical illness and low testosterone: Effects of human serum on testosterone transport in rat brain and liver. J. Clin. Endocrinol. Metab. 56: 710–714. 33 Corvol, P. & C. W. Bardin. 1973. Species distribution of testosterone-binding globulin. Biol. Reprod. 8: 277–282. 34 Bourget, C., C. Flood & C. Longcope. 1984. Steroid dynamics in the rabbit. Steroids 43: 225–233. 35 Gunsalus, G. L., N. A. Musto & C. W. Bardin. 1978. Immunoassay of androgen binding protein: A new approach to the study of the seminiferous tubule. Science 200: 65–67. 36 Chaudhuri, G., K. A. Steingold, W. M. Pardridge & H. L. Judd. 1988. TeBG-Bound and CBG-bound steroid hormones in rabbits are available for influx into uterus in vivo. Am. J. Physiol. 254: E79–E83. 37 Sakiyama, R., W. M. Pardridge & H. L. Judd. 1982. Effects of human cirrhotic serum on estradiol and testosterone transport into rat brain. J. Clin. Endocrinol. Metab. 54: 1140–1144. 38 Gordon, G. G., J. Olivo, F. Rafii & A. L. Southren. 1975. Conversion of androgens to estrogens in cirrhosis of the liver. J. Clin. Endocrinol. Metab. 40: 1018–1026. 39 Olivo, J., G. G. Gordon, F. Rafii & A. L. Southren. 1975. Estrogen metabolism in hyperthyroidism and in cirrhosis of the liver. Steroids 26: 47–56. 40 Van Thiel, D. H., J. S. Gavaler, R. Lester, D. L. Loriaux & G. D. Braunstein. 1975. Plasma estrone, prolactin, neurophysin, and sex steroid-binding globulin in chronic alcoholic men. Metabolism 24: 1015–1019. 41 Petra, P. H., F. Z. Stanczyk, D. F. Senear, P. C. Namkung, M. J. Now, J. B. A. Ross, E. Turner & J. A. Brown. 1983. Current status of the molecular structure and function of the plasma sex steroid-binding protein (SBP). J. Steroid Biochem. 19: 699–706. 42 Terasaki, T. & W. M. Pardridge. 1988. Differential binding of thyroxine and triiodothyronine to acidic isoforms of thyorid hormone binding globulin in human sera. Biochemistry 27: 3624–3628. 43 Terasaki, T., D. M. Knowlin & W. M. Pardridge. 1988. Differential binding of testosterone and estradiol to isoforms of SHBG: selective alteration of estradiol binding in cirrhosis. J. Clin. Endocrinol. Metab. 67. in press. 44 Van Theil, D. H. 1979. Feminization of chronic alcoholic men: A formulation. Yale J. Biol. Med. 52: 219–225. 45 Riad-Fahmy, D., G. F. Read & K. Griffiths. 1982. Steroids in saliva for assessing endocrine function. Endocr. Rev. 3: 367–395. 46 Setchell, B. P. & G. M. H. Waites. 1975. The blood-testis barrier. In Handbook of Physiology: Endrocrinology–Male Reproductive System. R. O. Greep & E. B. Astwood, Eds. 143–172. American Physiology Society. Washington , DC . 47 Pardridge, W. M., J. Eisenberg, G. Fierer & R. W. Kuhn. 1986. CBG does not restrict blood-brain barrier corticosterone transport in the rabbit. Am. J. Physiol. 251: E2O4–E208. 48 Pardridge, W. M., J. Eisenberg, G. Fierer & N. A. Musto. 1988. Developmental changes in brain and serum binding of testosterone and in brain capillary uptake of testosterone binding serum proteins in the rabbit. Dev. Brain Res. 38: 245–254. 49 Griffin, J. E. & J. D. Wilson. 1985. Disorders of the testes and male reproductive tract. In William's Textbook of Endocrinology. J. D. Wilson & D. W. Foster, Eds. 259–311. Saunders. Philadelphia , PA . 50 Pardridge, W. M. 1986. Serum bioavailability of sex steroid hormones. Clin. Endocrinol. Metab. 15: 259–278. 51 Vermeulen, A. & S. Ando. 1979. Metabolic clearance rate and interconversion of an-drogens and the influence of the free androgen fraction. J. Clin. Endocrinol. Metab. 48: 320–326. 52 Mahoudea, J. A., P. Corvol & H. Bricaire. 1973. Rabbit testosterone-binding globulin. II. Effect on androgen metabolism in vivo. Endocrinology 92: 1120–1125. 53 Terasaki, T., W. M. Pardridge & D. D. Denson. 1986. Differential effects of plasma protein binding of bupivacaine on its in vivo transfer into the brain and salivary gland of rats. J. Pharmacol. Exp. Ther. 239: 724–729. Citing Literature Volume538, Issue1Steroid‐Protein Interactions: Basic and Clinical Aspects Second International Symposium on Binding ProteinsSeptember 1988Pages 173-192 ReferencesRelatedInformation