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THE IMPACT OF OBESITY ON HEALTH RELATED QUALITY OF LIFE BEFORE AND AFTER RADICAL PROSTATECTOMY (DATA FROM CaPSURE)

2005; Lippincott Williams & Wilkins; Volume: 173; Issue: 4 Linguagem: Inglês

10.1097/01.ju.0000154973.38301.7f

1527-3792

Jason W. Anast, Natalia Sadetsky, David J. Pasta, William W. Bassett, David Latini, Janeen DuChane, June M. Chan, Matthew R. Cooperberg, Peter R. Carroll, Christopher J. Kane,

Urinary Bladder and Prostate Research

No AccessJournal of UrologyAdult Urology: Oncology: Prostate/Testis/Penis/Urethra1 Apr 2005THE IMPACT OF OBESITY ON HEALTH RELATED QUALITY OF LIFE BEFORE AND AFTER RADICAL PROSTATECTOMY (DATA FROM CaPSURE) JASON W. ANAST, NATALIA SADETSKY, DAVID J. PASTA, WILLIAM W. BASSETT, DAVID LATINI, JANEEN DuCHANE, JUNE M. CHAN, MATTHEW R. COOPERBERG, PETER R. CARROLL, and CHRISTOPHER J. KANE JASON W. ANASTJASON W. ANAST , NATALIA SADETSKYNATALIA SADETSKY , DAVID J. PASTADAVID J. PASTA , WILLIAM W. BASSETTWILLIAM W. BASSETT , DAVID LATINIDAVID LATINI , JANEEN DuCHANEJANEEN DuCHANE , JUNE M. CHANJUNE M. CHAN , MATTHEW R. COOPERBERGMATTHEW R. COOPERBERG , PETER R. CARROLLPETER R. CARROLL , and CHRISTOPHER J. KANECHRISTOPHER J. KANE View All Author Informationhttps://doi.org/10.1097/01.ju.0000154973.38301.7fAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Health related quality of life (HRQOL) is an important measure of outcomes among patients with prostate cancer due to disease related and treatment related effects on physical and emotional health. We determined if there are differences in the HRQOL of obese men at diagnosis and after radical prostatectomy compared to the HRQOL of men with normal body mass index (BMI). Materials and Methods: Data were abstracted from Cancer of the Prostate Strategic Urological Research Endeavor (CaPSURE), a disease registry of 10,018 men with prostate cancer. A total of 1,884 men were included in study who were treated with radical prostatectomy between 1989 and 2002, had BMI information available and had completed 1 initial HRQOL questionnaire. Of these men 672 who completed at least 2 followup questionnaires were assessed further. Results: The BMI (kg/m2) distributions were 24% normal (less than 24.9 kg/m2), 56% overweight (25 to 29.9), 16% obese (30 to 34.9) and 4% very obese (greater than 35 kg/m2). Higher BMI was associated with worse physical function, bodily pain, general health, vitality and role physical, but better bowel bother at diagnosis independent of race. Higher BMI was also associated with worse HRQOL after radical prostatectomy for physical function, general health and vitality, but better bowel bother. HRQOL differences between BMI groups were similar among times for all measured variables. Compared to the normal group, the higher BMI groups had similar HRQOL after radical prostatectomy. Conclusions: In the majority of domains men with higher BMI had lower HRQOL at diagnosis than men of normal BMI. 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Zion Comprehensive Cancer Center, University of California, San Francisco (JWA, NS, DJP, WWB, DL, JMC, MRC, PRC, CJK), Department of Urology, Veteran's Affairs Medical Center (JWA, WWB, CJK), San Francisco, California, and TAP Pharmaceutical Products, Inc., Lake Forest, Illinois (JD)© 2005 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byWolin K, Luly J, Sutcliffe S, Andriole G and Kibel A (2009) Risk of Urinary Incontinence Following Prostatectomy: The Role of Physical Activity and ObesityJournal of Urology, VOL. 183, NO. 2, (629-633), Online publication date: 1-Feb-2010.Montgomery J, Gayed B, Hollenbeck B, Daignault S, Sanda M, Montie J and Wei J (2018) Obesity Adversely Affects Health Related Quality of Life Before and After Radical Retropubic ProstatectomyJournal of Urology, VOL. 176, NO. 1, (257-262), Online publication date: 1-Jul-2006. Volume 173Issue 4April 2005Page: 1132-1138 Advertisement Copyright & Permissions© 2005 by American Urological Association, Inc.Keywordsobesityprostatectomyprostatic neoplasmsquality of lifeMetrics Author Information JASON W. ANAST More articles by this author NATALIA SADETSKY More articles by this author DAVID J. PASTA More articles by this author WILLIAM W. BASSETT More articles by this author DAVID LATINI More articles by this author JANEEN DuCHANE More articles by this author JUNE M. CHAN More articles by this author MATTHEW R. COOPERBERG More articles by this author PETER R. CARROLL More articles by this author CHRISTOPHER J. KANE More articles by this author Expand All Advertisement PDF downloadLoading ...