Portal de Periódicos da CAPES

The Escherichia coli metD Locus Encodes an ABC Transporter Which Includes Abc (MetN), YaeE (MetI), and YaeC (MetQ)

2002; American Society for Microbiology; Volume: 184; Issue: 19 Linguagem: Inglês

10.1128/jb.184.19.5513-5517.2002

1098-5530

Christophe Merlin, Gregory Gardiner, Sylvain Durand, Millicent Masters,

Antibiotic Resistance in Bacteria

ABSTRACT We report that the genes abc , yaeC , and yaeE comprise metD , an Escherichia coli locus encoding a dl -methionine uptake system. MetD is an ABC transporter with Abc the ATPase, YaeE the permease, and YaeC the likely substrate binding protein. Expression of these genes is regulated by l -methionine and MetJ, a common repressor of the methionine regulon. We propose to rename abc , yaeE , and yaeC as metN , metI , and metQ , respectively.