Artigo Acesso aberto Revisado por pares

CMV infection of liver transplant recipients: comparison of antigenemia and molecular biology assays

2001; BioMed Central; Volume: 1; Issue: 1 Linguagem: Inglês

10.1186/1471-2334-1-2

ISSN

1471-2334

Autores

Maria Luı́s Amorim, José Manuel Cabeda, R. Seca, Ana Constança Mendes, Ana Paula Castro, José Manuel Amorim,

Tópico(s)

Hepatitis Viruses Studies and Epidemiology

Resumo

CMV is a major clinical problem in transplant recipients. Thus, it is important to use sensitive and specific diagnostic techniques to rapidly and accurately detect CMV infection and identify patients at risk of developing CMV disease. In the present study, CMV infection after liver transplantation was monitored retrospectively by two molecular biology assays - a quantitative PCR assay and a qualitative NASBA assay. The results were compared with those obtained by prospective pp65 antigenemia determinations.

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