CMV infection of liver transplant recipients: comparison of antigenemia and molecular biology assays
2001; BioMed Central; Volume: 1; Issue: 1 Linguagem: Inglês
10.1186/1471-2334-1-2
ISSN1471-2334
AutoresMaria Luı́s Amorim, José Manuel Cabeda, R. Seca, Ana Constança Mendes, Ana Paula Castro, José Manuel Amorim,
Tópico(s)Hepatitis Viruses Studies and Epidemiology
ResumoCMV is a major clinical problem in transplant recipients. Thus, it is important to use sensitive and specific diagnostic techniques to rapidly and accurately detect CMV infection and identify patients at risk of developing CMV disease. In the present study, CMV infection after liver transplantation was monitored retrospectively by two molecular biology assays - a quantitative PCR assay and a qualitative NASBA assay. The results were compared with those obtained by prospective pp65 antigenemia determinations.
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