Perinuclear Mitochondrial Clustering Creates an Oxidant-Rich Nuclear Domain Required for Hypoxia-Induced Transcription
2012; American Association for the Advancement of Science; Volume: 5; Issue: 231 Linguagem: Inglês
10.1126/scisignal.2002712
ISSN1937-9145
AutoresAbu‐Bakr Al‐Mehdi, Viktor M. Pastukh, Brad M. Swiger, Darla Reed, Mita Patel, Gina C. Bardwell, Viktoriya Pastukh, Mikhail Alexeyev, Mark N. Gillespie,
Tópico(s)RNA modifications and cancer
ResumoReactive oxygen species generated by mitochondria that redistribute near the nucleus promote transcriptional responses to hypoxia.
Referência(s)