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Acute hemolytic anemia as a presenting manifestation of Wilson disease

1975; Elsevier BV; Volume: 86; Issue: 2 Linguagem: Inglês

10.1016/s0022-3476(75)80480-x

1097-6833

George R. Buchanan,

Iron Metabolism and Disorders

IT HAS RECENTLY BEEN DEMONSTRATED t h a t a seve re acu te hemoly t i c a n e m i a can on rare occas ion b e an early m a n i f e s t a t i o n o f W i l s o n disease ( h e p a t o l e n t icular degeneration).1-3 D e s c r i b e d in th is r epor t are two pa t ien ts , s e e n wi th in a 2 m o n t h per iod at the C h i l d r e n ' s Hospi ta l Medica l Cente r , w h o i l lustrate tha t Wi l son disease m u s t be c o n s i d e r e d in t he differential diagnosis o f acu te C o o m b s n e g a t i v e h e m o l y t i c a n e m i a in previous ly well ch i ld ren , e v e n in the a b s e n c e of clinically obv i ous l iver disease.