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Efficacy and Safety of Oxandrolone in Growth Hormone-Treated Girls with Turner Syndrome

2010; Oxford University Press; Volume: 95; Issue: 3 Linguagem: Inglês

10.1210/jc.2009-1821

1945-7197

Leonie A. Menke, Theo Sas, Sabine M.P.F. de Muinck Keizer‐Schrama, Gladys R.J. Zandwijken, Maria de Ridder, Roelof J. Odink, M. Jansen, Henriëtte A. Delemarre‐van de Waal, Wilhelmina H. Stokvis‐Brantsma, J. J. J. Waelkens, Ciska Westerlaken, H.M. Reeser, A.S. Paul van Trotsenburg, Evelien Gevers, Stef van Buuren, Philippe H. Dejonckere, Anita Hokken-Koelega, Barto J. Otten, Jan M. Wit,

Hypothalamic control of reproductive hormones

Context and Objective: GH therapy increases growth and adult height in Turner syndrome (TS). The benefit to risk ratio of adding the weak androgen oxandrolone (Ox) to GH is unclear.