Artigo Acesso aberto Revisado por pares

Impairment of BRCA1-Related DNA Double-Strand Break Repair Leads to Ovarian Aging in Mice and Humans

2013; American Association for the Advancement of Science; Volume: 5; Issue: 172 Linguagem: Inglês

10.1126/scitranslmed.3004925

ISSN

1946-6242

Autores

Shiny Titus, Fang Li, Robert Stobezki, Komala Akula, Evrim Ünsal, Kyungah Jeong, Maura N. Dickler, Mark E. Robson, Fred Moy, Sumanta Goswami, Kutluk Oktay,

Tópico(s)

Genetics, Aging, and Longevity in Model Organisms

Resumo

DNA double-strand break repair has a central role in oocyte aging.

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