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Capped mesoporous silica nanoparticles as stimuli-responsive controlled release systems for intracellular drug/gene delivery

2010; Taylor & Francis; Volume: 7; Issue: 9 Linguagem: Inglês

10.1517/17425247.2010.498816

1744-7593

Yannan Zhao, Juan L. Vivero‐Escoto, Igor I. Slowing, Brian G. Trewyn, Victor S.-Y. Lin,

Nanoparticle-Based Drug Delivery

Importance of the field: The incorporation of stimuli-responsive properties into nanostructured systems has recently attracted significant attention in the research of intracellular drug/gene delivery. In particular, numerous surface-functionalized, end-capped mesoporous silica nanoparticle (MSN) materials have been designed as efficient stimuli-responsive controlled release systems with the advantageous 'zero premature release' property.