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BIBTEX RIS

Enhancement of Diagnostic Efficiency by a Gamma Interferon Release Assay for Pulmonary Tuberculosis

2008; American Society for Microbiology; Volume: 15; Issue: 6 Linguagem: Inglês

10.1128/cvi.00026-08

ISSN

1556-6811

Autores

Kelly Aparecida Kanunfre, Olavo Henrique Munhoz Leite, Max Igor Banks Ferreira Lopes, Marcelo Nóbrega Litvoc, Antônio Walter Ferreira,

Tópico(s)

Diagnosis and treatment of tuberculosis

Resumo

ABSTRACT This study was designed to examine the use of the QuantiFERON-TB Gold assay as an aid in the diagnosis of active pulmonary tuberculosis (TB) in Brazilian patients. Using the receiver operating characteristic curve, the cutoff was adjusted to ≥0.20 IU/ml. The sensitivity increased to 86%, with 100% specificity. All TB patients with negative sputum smear microscopy and negative culture results were positive using this test.

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