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BIBTEX RIS

Detection of bla SHV , bla TEM and bla CTX-M antibiotic resistance genes in randomly selected bacterial pathogens from the Steve Biko Academic Hospital

2009; Oxford University Press; Volume: 56; Issue: 3 Linguagem: Inglês

10.1111/j.1574-695x.2009.00564.x

ISSN

1574-695X

Autores

Marthie M. Ehlers, Chrisna Veldsman, Eddy P. Makgotlho, Michael G. Dove, A A Hoosen, Marleen M. Kock,

Tópico(s)

Salmonella and Campylobacter epidemiology

Resumo

Extended-spectrum beta-lactamases (ESBLs) are considered to be one of the most important antibiotic resistance mechanisms. This study reported the ESBL-producing genes in 53 randomly selected clinical bacterial isolates from the Steve Biko Academic Hospital. The presence of the bla(SHV), bla(TEM) and bla(CTX-M) genes was determined, and the overall prevalence of these genes detected in this study was 87% (46/53) in comparison with the literature; these results were higher when compared with 33% for Escherichia coli in Europe and 0.8% in Denmark for similar pathogens. These research findings indicated that it is crucial to routinely monitor the prevalence of these resistance genes.

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