Toward (Z)-selective Horner–Wadsworth–Emmons reaction of aldehydes with 2-fluoro-2-diethylphosphonoacetic acid
2002; Elsevier BV; Volume: 43; Issue: 50 Linguagem: Inglês
10.1016/s0040-4039(02)02269-4
ISSN1873-3581
AutoresShigeki Sano, Rie Teranishi, Yoshimitsu Nagao,
Tópico(s)Synthesis and Reactivity of Sulfur-Containing Compounds
ResumoThe stereoselective Horner–Wadsworth–Emmons reaction of aldehydes with 2-fluoro-2-diethylphosphonoacetic acid utilizing i-PrMgBr afforded (Z)-α-fluoro-α,β-unsaturated carboxylic acids as the major products.
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