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Congenital Intracranial Mesenchymal Chondrosarcoma: Case Report and Review of the Literature in Pediatric Patients

2008; SAGE Publishing; Volume: 11; Issue: 4 Linguagem: Inglês

10.2350/07-05-0279.1

1615-5742

Rossella De Cecio, Ilenia Migliaccio, Jessica Falleti, Marialaura Basso Del De, Guido Pettinato,

Oral and Maxillofacial Pathology

In this paper we report the 1st case of a congenital intracranial mesenchymal chondrosarcoma in a 2-month-old infant, apparently present at birth. A magnetic resonance image showed a large left parietal solid mass, while microscopy revealed a mixture of undifferentiated small cells and mature hyaline cartilage islands, positive for vimentin, S-100, and CD99. A surgical excision was performed but the patient died after a few weeks as a result of a rapid relapse of the tumor. We also review the pediatric cases (in patients less than 20 years old) of extraskeletal (intracranial) mesenchymal chondrosarcomas of the literature, with a focus on the most recent cytogenetic and immunohistochemical studies.