Chronological diffusion-weighted imaging changes and mutism in the course of rotavirus-associated acute cerebellitis/cerebellopathy concurrent with encephalitis/encephalopathy
2010; Elsevier BV; Volume: 33; Issue: 1 Linguagem: Inglês
10.1016/j.braindev.2010.04.007
ISSN1872-7131
AutoresTetsuo Kubota, Toshihiko Suzuki, Yuma Kitase, Hiroyuki Kidokoro, Yuji Miyajima, Akimasa Ogawa, Jun Natsume, Akihisa Okumura,
Tópico(s)Viral gastroenteritis research and epidemiology
ResumoRotavirus is one of the most common causes of gastroenteritis in children and is known to accompany some neurological disorders such as encephalitis/encephalopathy and seizures. Although cerebellar disorders sometime occur as a complication of rotavirus gastroenteritis in Japan, few reports have addressed these issues. Here, we report three cases of insulted cerebellums in addition to encephalitis/encephalopathy associated with rotavirus. Similar to posterior fossa syndrome after surgery, mutism was a notable symptom that lasted about 1 month. Brain diffusion-weighted imaging (DWI) revealed chronological changes, i.e., marked hyperintensity in the bilateral dentate nucleus followed by the vermis and cerebellar hemisphere. The bilateral dentate nucleus is known to be a key lesion site for mutism, and these clinical and radiological findings may be tightly connected in rotavirus-associated cerebellitis/cerebellopathy.
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