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BIBTEX RIS

Mechanisms of virus uncoating

1994; Elsevier BV; Volume: 2; Issue: 2 Linguagem: Inglês

10.1016/0966-842x(94)90126-0

ISSN

1878-4380

Autores

Urs F. Greber, Ila Singh, Ari Helenius,

Tópico(s)

Animal Virus Infections Studies

Resumo

In a virus particle, the genome is highly condensed and protected by proteins and membrane bilayers. Before it can be replicated in a new host cell, uncoating must take place. Recent studies on enveloped and nonenveloped animal viruses indicate that uncoating occurs through complex, multistep processes triggered by virus-host-cell interactions.

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