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Long-term Persistence of Zoster Vaccine Efficacy

2014; Oxford University Press; Volume: 60; Issue: 6 Linguagem: Inglês

10.1093/cid/ciu918

1537-6591

Vicki A. Morrison, Gary R. Johnson, Kenneth E. Schmader, Myron J. Levin, Jane H. Zhang, David J. Looney, Robert F. Betts, Larry Gelb, John Guatelli, Ruth Harbecke, Connie Pachucki, Susan Keay, Barbara E. Menzies, Marie R. Griffin, Carol A. Kauffman, Adriana Marques, John Toney, Kathy D. Boardman, Shu‐Chih Su, Xiaoming Li, Ivan S. F. Chan, Janie Parrino, Paula W. Annunziato, Michael N. Oxman, LE. Davis, CA Kauffman, S. Keay, SE Straus, AR Marques, NE Soto, P. A. Brunell, J. W. Gnann, Rosário Serrão, D. J. Cotton, R.P. Goodman, RD Arbeit, C. T. Pachucki, M J Levin, KE Schmader, W Keitel, RN Greenberg, VA Morrison, PF Wright, MR Griffin, MS Simberkoff, S-s Yeh, Zeena Lobo, Mark Holodniy, J. F. Loutit, Betts Rf, LD Gelb, G. E. Crawford, J C Guatelli, Paul Brooks, D. J. Looney, K M Neuzil, JF Toney, CA Kauffman, S. Keay, AR Marques, C. T. Pachucki, M J Levin, KE Schmader, VA Morrison, PF Wright, MR Griffin, Betts Rf, LD Gelb, J C Guatelli, D. J. Looney, K M Neuzil, B Menzies, JF Toney,

Bartonella species infections research

Background. The Shingles Prevention Study (SPS) demonstrated zoster vaccine efficacy through 4 years postvaccination. A Short-Term Persistence Substudy (STPS) demonstrated persistence of vaccine efficacy for at least 5 years. A Long-Term Persistence Substudy (LTPS) was undertaken to further assess vaccine efficacy in SPS vaccine recipients followed for up to 11 years postvaccination. Study outcomes were assessed for the entire LTPS period and for each year from 7 to 11 years postvaccination.