Artigo Acesso aberto Produção Nacional Revisado por pares

Prevalence of human papillomavirus in penile malignant tumors: viral genotyping and clinical aspects

2015; BioMed Central; Volume: 15; Issue: 1 Linguagem: Inglês

10.1186/s12894-015-0007-8

ISSN

1471-2490

Autores

Isaura Danielli Borges de Sousa, Flávia Castello Branco Vidal, João Paulo Castello Branco Vidal, George Castro Figueira de Mello, Maria do Desterro Soares Brandão Nascimen, Luciane Maria Oliveira Brito,

Tópico(s)

Urological Disorders and Treatments

Resumo

The human papillomavirus (HPV) prevalence in males has been reported to be between 3.6% and 84%, depending specially on the socioeconomic status. HPV infection has been related as a risk factor for penile cancer. This is a rare tumor, and other risk factors include lack of personal hygiene and men who have not undergone circumcision. Penile cancer is less than 1% of cancers in men in the United States, however, is much more common in some parts of Asia, Africa, and South America, where it accounts for up to 10% of cancers in men. This study aimed to determine the prevalence of HPV-DNA in penile cancers in São Luís, Brazil and to correlate the virus presence to histopathological factors.

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