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Probing the Relevance of NHC Ligand Conformations in the Ru‐Catalysed Ring‐Closing Metathesis Reaction

2013; Wiley; Volume: 19; Issue: 32 Linguagem: Inglês

10.1002/chem.201301540

1521-3765

Alessandra Perfetto, Chiara Costabile, Pasquale Longo, V. Bertolasi, Fabia Grisi,

N-Heterocyclic Carbenes in Organic and Inorganic Chemistry

Cat power: Judicious backbone substitution of N-heterocyclic carbenes (NHCs) leads to stable Ru metathesis catalysts with frozen NHC conformations. This finding not only permits the isolation of complexes that are among the most active catalysts in the ring-closing metathesis of hindered olefins (see graphic; Ts=p-toluenesulfonyl), but also provides fundamental mechanistic insights on the role of N-aryl substituent conformations on catalyst activity. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.