Artigo Produção Nacional

ESTUDO DA AÇÃO DE Nicotiana glauca GRAHAM (ERVA PARAGUAIA) COMO COADJUVANTE EM VACINA CONTRA A DOENÇA DE NEWCASTLE EM FRANGOS DE CORTE

2008; UNIVERSIDADE FEDERAL DE GOIÁS; Volume: 9; Issue: 2 Linguagem: Inglês

10.5216/cab.v9i2.1086

ISSN

1809-6891

Autores

Marlete Brum Cleff, Geferson Fischer, Caren Gularte Quincozes, M. A. Anciuti, Rogério Antônio Freitag, Telmo Vidor, Fabiane Pereira Gentilini, Carlos Eduardo Wayne Nogueira,

Tópico(s)

Toxin Mechanisms and Immunotoxins

Resumo

The Nicotiana glauca is a native plant species from Argentina, but found all over South America, being used against headaches, rheumatism, injuries, ulcers, and so on. Researchers have considered it as having immunomodulation effect. This study was conducted to investigate the use of a aqueous extract of Nicotiana glauca Graham as an immunomodulator (adjuvant) of a Newcastle disease vaccine.. A total of 56 broilers were distributed into 4 experimental groups. Each one of them received 3 dosages of this vaccine with or without the addition of different concentrations of the extract Using hemmoaglutination inhibition techniques , the results have shown differences (P 0.05) from Treatment 1. These results indicated that further investigations are required, including the use of cytotoxicity tests in vitro, to evaluate the immunomodulation effect of this extract. KEY WORDS: Immunomodulation effect, Nicotiana glauca Graham, vaccine.

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