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Nanostructuring of Patterned Microelectrodes To Enhance the Sensitivity of Electrochemical Nucleic Acids Detection

2009; Wiley; Volume: 48; Issue: 45 Linguagem: Inglês

10.1002/anie.200902439

1521-3773

Leyla Soleymani, Zhichao Fang, Xuping Sun, Hong Yang, Bradford J. Taft, Edward H. Sargent, Shana O. Kelley,

Electrochemical Analysis and Applications

Take the rough without the smooth: The electrodeposition of patterned metal microelectrodes on a chip-based platform led to biosensors with varying sensitivity according to the degree of surface nanostructuring, which could be controlled systematically (see picture). The sensitivity of microelectrodes with highly nanostructured surfaces was superior to that of smooth microelectrodes. Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.