Artigo Acesso aberto Produção Nacional Revisado por pares

Xanthium strumarium L. antimicrobial activity and carboxyatractyloside analysis through electrospray ionization mass spectrometry

2009; UNIVERSIDADE EST.PAULISTA JÚLIO DE MESQUITA FILHO; Volume: 11; Issue: 2 Linguagem: Inglês

10.1590/s1516-05722009000200008

ISSN

1983-084X

Autores

Rodrigo Scherer, Marta Cristina Teixeira Duarte, Rodrigo Ramos Catharino, Fabiane M. Nachtigall, Marcos N. Eberlin, José Teixeira Filho, Helena Teixeira Godoy,

Tópico(s)

Natural product bioactivities and synthesis

Resumo

The aim of this work was to evaluate the antimicrobial activity of Xanthium strumarium L. leaf extracts against Staphylococcus aureus, Escherichia coli, Salmonella typhimurium, Pseudomonas aeruginosa and Clostridium perfringens, as well as to investigate the presence of the toxic compound carboxyatractyloside in different plant parts. S. aureus and C. perfringens were more sensitive to non-polar than to polar fractions, and there was no difference between extracts for the remaining bacteria. All extracts had strong antimicrobial activity against the evaluated microorganisms. Carboxyatractyloside was found in cotyledons and seeds but not in adult leaves and burrs. Thus, only Xanthium strumarium leaves in adult stage can be used for medicinal purposes.

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