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Patients receiving anti-TNF therapies experience clinically important improvements in RA-related fatigue: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis

2014; Oxford University Press; Volume: 54; Issue: 6 Linguagem: Inglês

10.1093/rheumatology/keu390

1462-0332

Katie L. Druce, Gareth T. Jones, Gary J. Macfarlane, Neil Basu,

Fibromyalgia and Chronic Fatigue Syndrome Research

Objectives. Pro-inflammatory cytokines such as TNF-α are important in the pathogenesis of fatigue in conditions such as RA. This study aimed to determine whether fatigue improved in a cohort of RA patients with clinically relevant fatigue commencing anti-TNF-α therapy and, if so, to identify predictors of improvement.