Iodine as a Catalyst for Efficient Conversion of Ketones to g em -Dihydroperoxides by Aqueous Hydrogen Peroxide
2006; American Chemical Society; Volume: 8; Issue: 12 Linguagem: Inglês
10.1021/ol060590r
ISSN1523-7060
AutoresKatja Žmitek, Marko Zupan, Stojan Stavber, Jernej Iskra,
Tópico(s)Vanadium and Halogenation Chemistry
ResumoIodine has been shown to be an efficient catalyst for the selective dihydroperoxidation of ketones with aqueous hydrogen peroxide. Ketones were directly converted to their corresponding gem-dihydroperoxides using a "green" oxidant (30% aq H(2)O(2)) and a simple catalyst (iodine) under neutral conditions in acetonitrile. The yield of hydroperoxidation of various cyclic ketones was 60-98% including androstane-3,17-dione, and acyclic ketones were converted with a similar efficiency. [reaction: see text]
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