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Abdominal wall healing in incisional hernia using different biomaterials in rabbits

2013; Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia; Volume: 28; Issue: 4 Linguagem: Inglês

10.1590/s0102-86502013000400011

1678-2674

Ana Letícia Gomes Aramayo, Gaspar de Jesus Lopes Filho, Cirênio de Almeida Barbosa, Vânia da Fonseca Amaral, Luciano Assis Costa,

Pelvic and Acetabular Injuries

PURPOSE: To investigate abdominal wound healing using specific biomaterials in incisional hernias. METHODS: Incisional hernias were produced in 40 rabbits, after that they were reoperated with or without the use of meshes: PREMILENE® (PPL), ULTRAPRO® (UP), PROCEED® (PCD) or repairing without mesh (TRANSPALB). After 30 days a macroscopic and microscopic study of the part withdrawn from the abdominal wall was performed. RESULTS: Macroscopic: adhesion Area: PPL> UP and PCD (p = 0.031). Vascularization: PPL> UP and PCD (p = 0.001). PPL groups (p = 0.032) and PCD (p PPL, UP and TRANSPALB (p = 0.010); eosinophils: PPL> UP, and TRANSPALB PCD (p = 0.010); granulation tissue: PPL and PCD> UP and TRANSPALB (p TRANSPALB (p UP (p = 0.009) and TRANSPALB (p TRANSPALB (p PCD and TRANSPALB (p <0.001). CONCLUSION: All types of meshes caused the formation of adhesions. The UP and PCD groups showed lower area and vascularization of the adhesions. The PPL and PCD groups showed higher meshes shrinkage and there was a predominance of acute inflammatory process in the PCD group.