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Diagnosis of Rapid Eye Movement Sleep Disorder With Electroencephalography and Treatment With Tricyclic Antidepressants in a Dog

2004; American Animal Hospital Association; Volume: 40; Issue: 6 Linguagem: Inglês

10.5326/0400495

1547-3317

William W. Bush, Christina S. Barr, Mark M. Stecker, Karen L. Overall, Noemie M. Bernier, Edwin W. Darrin, Adrian R. Morrison,

Neuroscience of respiration and sleep

A 9-month-old, female Labrador retriever mix was presented for two types of seizure-like episodes, one of which occurred only during sleep. The two types of episodes were morphologically distinct. An electroencephalogram (EEG) demonstrated that the sleep-associated episodes occurred during rapid eye movement (REM) sleep, supporting a diagnosis of a REM behavior disorder. Based on their morphology and response to antiseizure medications, the waking episodes were diagnosed as seizures. The animal was also diagnosed with an obsessive-compulsive and generalized anxiety disorder. The REM behavior disorder and anxiety-related behaviors improved with tricyclic antidepressant therapy.