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Complementation of human adenovirus type 5 ts mutants by human adenovirus type 12

1975; American Society for Microbiology; Volume: 15; Issue: 3 Linguagem: Inglês

10.1128/jvi.15.3.675-678.1975

1098-5514

J. F. Williams, Howard A. Young, Paul Tran Austin,

CAR-T cell therapy research

Temperature-sensitive mutants of type 5 adenovirus belonging to eight complementation groups were complemented in mixed infection by type 12 adenovirus, whereas mutants of 7 other groups were not enhanced. In some crosses, phenotypic mixing took place. No evidence of recombination between type 5 ts mutants and type 12 was found.