Inverted Piano Stools: A Molecular Recognition Motif That Enforces 1:1 Cocrystallization of Two Diastereomers in the Same Single Crystal
2003; Wiley; Volume: 42; Issue: 16 Linguagem: Inglês
10.1002/anie.200250181
ISSN1521-3773
AutoresHenri Brunner, Matthias Weber, Manfred Zabel, Thomas Zwack,
Tópico(s)Chemical Synthesis and Analysis
ResumoHalf-sandwich complexes of the type [(Ar)MXY(NR*)] (see structure; X, Y=electronegative substituents; M=Ru, Os, Rh, Ir) tend to form inversion pairs in the solid state, which are characterized by short M⋅⋅⋅M separations and CH⋅⋅⋅X/Y hydrogen bonds between the pairs of molecules. As a consequence, two diastereomers with a given chirality in the Z substituent, usually an NR* substituent, and different metal configurations approach each other with their “racemic sides” resulting in an unusually preferred 1:1 diastereomer cocrystallization in the same single crystal.
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