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The prevalence of Neisseria gonorrhoeae negative for proline iminopeptidase in Asturias, Spain

2006; BMJ; Volume: 83; Issue: 1 Linguagem: Inglês

10.1136/sti.2006.022699

1472-3263

Luís Otero, Marta Elena Álvarez‐Argüelles, Hugo Edgardo Villar, J Diaz-Gigante, Francisca Carreño, Fernando Vázquez,

Peptidase Inhibition and Analysis

Alexander et al 1 have recently reported the prevalence of Neisseria gonorrhoeae negative for proline iminopeptidase (Pip) in England and Wales. This is a considerable problem given that many commercial biochemical test panels (Gonochek II, API NH or RapidID NH) monitor the presence of this enzyme and generate a false-negative identification.1–3 As data are scarce, we present our findings of the past 4 years. A total of 143 isolates from consecutive patients were received during a 4-year period (2003–2006) at the Regional Laboratory for Gonococci, Hospital Monte Naranco, Oviedo, Spain. This unit receives all the isolates of N gonorrhoeae in Asturias, a regional county in the north of Spain with a population of …