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BIBTEX RIS

High Susceptibility of Human Dendritic Cells to Invasion by the Intracellular Pathogens Brucella suis, B. abortus , and B. melitensis

2005; American Society for Microbiology; Volume: 73; Issue: 12 Linguagem: Inglês

10.1128/iai.73.12.8418-8424.2005

ISSN

1098-5522

Autores

Elisabeth Billard, Chantal Cazevieille, Jacques Dornand, Antoine Gross,

Tópico(s)

Galectins and Cancer Biology

Resumo

Bacteria from the Brucella genus are able to survive and proliferate within macrophages. Because they are phylogenetically closely related to macrophages, myeloid dendritic cells (DCs) constitute potential targets for Brucella bacteria. Here we report that DCs display a great susceptibility to Brucella infection. Therefore, DCs might serve as a reservoir and be important for the development of Brucella bacteria within their host.

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