Portal de Periódicos da CAPES

Validation of the Spanish, Portuguese and French versions of the Lupus Damage Index questionnaire: data from North and South America, Spain and Portugal

2009; SAGE Publishing; Volume: 18; Issue: 12 Linguagem: Inglês

10.1177/0961203309105590

1477-0962

Bernardo A. Pons‐Estel, Jorge Sánchez‐Guerrero, Juanita Romero‐Díaz, Antonio Iglesias Gamarra, Eloísa Bonfá, Eduardo Ferreira Borba, Samuel Katsuyuki Shinjo, Sasha Bernatsky, Ann E. Clarke, Mercedes García, J.R. Gonzlez Marcos, Ana Joana Duarte, GA Berbotto, H R Scherbarth, CD Marques, Laura Onetti, Verónica Saurit, AWS Souza, E. Velozo, Luís J. Catoggio, Óscar Neira, Paula I. Burgos, L. Ramirez, JF Molina, IG De La Torre, Ricardo Silvariño, J Manni, Sergio Durán-Barragán, LM Vilá, Paul R. Fortin, Jaime Calvo‐Alén, María José Santos, Mariana Portela, MH Esteva-Spinetti, Michael H. Weisman, EM Acevedo, MI Segami, SB Gentiletti, José F. Roldán, Iris Navarro‐Millán, Esther Rubio González, J. M. Liu, EW Karlson, KH Costenbader, Frederick Wolfe, Alarcón Gs,

Cytokine Signaling Pathways and Interactions

We have previously developed and validated a self-administered questionnaire, modelled after the Systemic Lupus International Collaborating Clinics Damage Index (SDI), the Lupus Damage Index Questionnaire (LDIQ), which may allow the ascertainment of this construct in systemic lupus erythematosus (SLE) patients followed in the community and thus expand observations made about damage. We have now translated, back-translated and adapted the LDIQ to Spanish, Portuguese and French and applied it to patients followed at academic and non-academic centres in North and South America, Portugal and Spain while their physicians scored the SDI. A total of 887 patients (659 Spanish-speaking, 140 Portuguese-speaking and 80 French-speaking patients) and 40 physicians participated. Overall, patients scored all LDIQ versions higher than their physicians (total score and all domains). Infrequent manifestations had less optimal clinimetric properties but overall agreement was more than 95% for the majority of items. Higher correlations were observed among the Spanish-speaking patients than the Portuguese-speaking and French-speaking patients; further adjustments may be needed before the Portuguese and French versions of the LDIQ are applied in community-based studies. The relationship between the LDIQ and other outcome parameters is currently being investigated in a different patient sample.