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A Functional Toll-Like Receptor 3 Gene (TLR3) May Be a Risk Factor for Tick-borne Encephalitis Virus (TBEV) Infection

2011; Oxford University Press; Volume: 203; Issue: 4 Linguagem: Inglês

10.1093/infdis/jiq082

1537-6613

Elin Kindberg, Sirkka Vene, Auksė Mickienė, Åke Lundkvist, Lars Lindquist, Lennart Svensson,

Vector-borne infectious diseases

Background. Tick-borne encephalitis virus (TBEV) infections may be asymptomatic or cause severe symptoms in the central nervous system. A mutation in the chemokine receptor 5 gene has been associated with increased risk of TBE but explains only a limited number of cases. Investigations of further risk factors are needed.