Artigo Acesso aberto Produção Nacional Revisado por pares

Deep brain stimulation induces antiapoptotic and anti-inflammatory effects in epileptic rats

2015; BioMed Central; Volume: 12; Issue: 1 Linguagem: Inglês

10.1186/s12974-015-0384-7

ISSN

1742-2094

Autores

Beatriz Oliveira Amorim, Luciene Covolan, Elenn Soares Ferreira, José Geraldo Brito, Diego P. Nunes, David G. de Morais, José N. Nóbrega, Antônio Márcio Rodrigues, Antonio Carlos G. deAlmeida, Clement Hamani,

Tópico(s)

Neuroscience and Neural Engineering

Resumo

Status epilepticus (SE) is a severe condition that may lead to hippocampal cell loss and epileptogenesis. Some of the mechanisms associated with SE-induced cell death are excitotoxicity, neuroinflammation, and apoptosis.

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