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Organizing knowledge to enable personalization of medicine in cancer

2014; BioMed Central; Volume: 15; Issue: 8 Linguagem: Inglês

10.1186/s13059-014-0438-7

1474-760X

Benjamin M. Good, Benjamin J. Ainscough, Josh F. McMichael, Andrew I. Su, Obi L. Griffith,

Bioinformatics and Genomic Networks

Interpretation of the clinical significance of genomic alterations remains the most severe bottleneck preventing the realization of personalized medicine in cancer. We propose a knowledge commons to facilitate collaborative contributions and open discussion of clinical decision-making based on genomic events in cancer.