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Forensic implications of genetic analyses from degraded DNA—A review

2009; Elsevier BV; Volume: 4; Issue: 3 Linguagem: Inglês

10.1016/j.fsigen.2009.09.007

1878-0326

Reza Alaeddini, Simon J. Walsh, Ali Abbas,

Environmental DNA in Biodiversity Studies

Forensic DNA identification techniques are principally based on determination of the size or sequence of desired PCR products. The fragmentation of DNA templates or the structural modifications that can occur during the decomposition process can impact the outcomes of the analytical procedures. This study reviews the pathways involved in cell death and DNA decomposition and the subsequent difficulties these present in DNA analysis of degraded samples.