Portal de Periódicos da CAPES

Nuclease resistant oligonucleotides with cell penetrating properties

2015; Royal Society of Chemistry; Volume: 51; Issue: 19 Linguagem: Inglês

10.1039/c4cc08837a

1364-548X

Stefan Milton, Dmytro Honcharenko, Cristina S. J. Rocha, Pedro M. D. Moreno, Smith Rjh, Roger Strömberg,

RNA Interference and Gene Delivery

2′- O -AECM modified oligonucleotides provide a combination of remarkable properties, such as high stability towards degradation, stable duplexes with RNA and enhanced cellular uptake.