DNA–porphyrin interactions probed by induced CD spectroscopy

1994; Royal Society of Chemistry; Issue: 13 Linguagem: Inglês

10.1039/c39940001575

ISSN

2050-5639

Autores

Reiko Kuroda, Hajime Tanaka,

Tópico(s)

Surface Chemistry and Catalysis

Resumo

Detailed analysis by induced CD spectroscopy has revealed that the manganese porphyrin, Mn(tmpyp), binds the major groove of AT or GC sequences in DNA, as well as the reported minor groove of AT sequences, with a preference that depends on the porphyrin to DNA base-pair molar ratio.

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