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Research Highlights: Pulling out novel COPD genes from the ‘gray zone’ of genome-wide association studies

2012; Future Medicine; Volume: 9; Issue: 2 Linguagem: Inglês

10.2217/pme.12.7

1744-828X

Yohan Bossé,

Pediatric health and respiratory diseases

Personalized MedicineVol. 9, No. 2 News & ViewsResearch Highlights: Pulling out novel COPD genes from the 'gray zone' of genome-wide association studiesYohan BosséYohan BosséLaval University, Department of Molecular Medicine, Institut Universitaire de Cardiologie et de Pneumologie de Québec, Pavillon Marguerite-d'Youville, Y4190, 2725, Chemin Sainte-Foy, Québec, Canada. Published Online:6 Mar 2012https://doi.org/10.2217/pme.12.7AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInReddit View articleReferences1 Manolio TA. Genomewide association studies and assessment of the risk of disease. N. Engl. J. Med.363(2),166–176 (2010).Crossref, Medline, CAS, Google Scholar2 Brehm JM, Hagiwara K, Tesfaigzi Y et al. Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease. Thorax66(12),1085–1090 (2011).Crossref, Medline, Google Scholar3 Miyazawa H, Kato M, Awata T et al. Homozygosity haplotype allows a genomewide search for the autosomal segments shared among patients. Am. J. Hum. Genet.80(6),1090–1102 (2007).Crossref, Medline, CAS, Google Scholar4 Cho MH, Boutaoui N, Klanderman BJ et al. Variants in FAM13A are associated with chronic obstructive pulmonary disease. Nat. Genet.42(3),200–202 (2010).Crossref, Medline, CAS, Google Scholar5 Cookson W, Liang L, Abecasis G, Moffatt M, Lathrop M. Mapping complex disease traits with global gene expression. Nat. Rev. Genet.10(3),184–194 (2009).Crossref, Medline, CAS, Google ScholarReferences1 Manolio TA. Genomewide association studies and assessment of the risk of disease. N. Engl. J. Med.363(2),166–176 (2010).Crossref, Medline, CAS, Google Scholar2 Brehm JM, Hagiwara K, Tesfaigzi Y et al. Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease. Thorax66(12),1085–1090 (2011).Crossref, Medline, Google Scholar3 Miyazawa H, Kato M, Awata T et al. Homozygosity haplotype allows a genomewide search for the autosomal segments shared among patients. Am. J. Hum. Genet.80(6),1090–1102 (2007).Crossref, Medline, CAS, Google Scholar4 Cho MH, Boutaoui N, Klanderman BJ et al. Variants in FAM13A are associated with chronic obstructive pulmonary disease. Nat. Genet.42(3),200–202 (2010).Crossref, Medline, CAS, Google Scholar5 Cookson W, Liang L, Abecasis G, Moffatt M, Lathrop M. Mapping complex disease traits with global gene expression. Nat. Rev. Genet.10(3),184–194 (2009).Crossref, Medline, CAS, Google ScholarReferences1 Manolio TA. Genomewide association studies and assessment of the risk of disease. N. Engl. J. Med.363(2),166–176 (2010).Crossref, Medline, CAS, Google Scholar2 Brehm JM, Hagiwara K, Tesfaigzi Y et al. Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease. Thorax66(12),1085–1090 (2011).Crossref, Medline, Google Scholar3 Miyazawa H, Kato M, Awata T et al. Homozygosity haplotype allows a genomewide search for the autosomal segments shared among patients. Am. J. Hum. Genet.80(6),1090–1102 (2007).Crossref, Medline, CAS, Google Scholar4 Cho MH, Boutaoui N, Klanderman BJ et al. Variants in FAM13A are associated with chronic obstructive pulmonary disease. Nat. Genet.42(3),200–202 (2010).Crossref, Medline, CAS, Google Scholar5 Cookson W, Liang L, Abecasis G, Moffatt M, Lathrop M. Mapping complex disease traits with global gene expression. Nat. Rev. Genet.10(3),184–194 (2009).Crossref, Medline, CAS, Google ScholarReferences1 Manolio TA. Genomewide association studies and assessment of the risk of disease. N. Engl. J. Med.363(2),166–176 (2010).Crossref, Medline, CAS, Google Scholar2 Brehm JM, Hagiwara K, Tesfaigzi Y et al. Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease. Thorax66(12),1085–1090 (2011).Crossref, Medline, Google Scholar3 Miyazawa H, Kato M, Awata T et al. Homozygosity haplotype allows a genomewide search for the autosomal segments shared among patients. Am. J. Hum. Genet.80(6),1090–1102 (2007).Crossref, Medline, CAS, Google Scholar4 Cho MH, Boutaoui N, Klanderman BJ et al. Variants in FAM13A are associated with chronic obstructive pulmonary disease. Nat. Genet.42(3),200–202 (2010).Crossref, Medline, CAS, Google Scholar5 Cookson W, Liang L, Abecasis G, Moffatt M, Lathrop M. Mapping complex disease traits with global gene expression. Nat. Rev. Genet.10(3),184–194 (2009).Crossref, Medline, CAS, Google ScholarFiguresReferencesRelatedDetails Vol. 9, No. 2 Follow us on social media for the latest updates Metrics Downloaded 97 times History Published online 6 March 2012 Published in print March 2012 Information© Future Medicine LtdPDF download