Artigo Acesso aberto Revisado por pares

Designer emulsions using microfluidics

2008; Elsevier BV; Volume: 11; Issue: 4 Linguagem: Inglês

10.1016/s1369-7021(08)70053-1

ISSN

1873-4103

Autores

Rhutesh K. Shah, Ho Cheung Shum, Amy C. Rowat, Daeyeon Lee, Jeremy J. Agresti, Andrew S. Utada, Liang‐Yin Chu, Jin Woong Kim, Alberto Fernández‐Nieves, Carlos J. Martinez, David A. Weitz,

Tópico(s)

Microfluidic and Capillary Electrophoresis Applications

Resumo

We describe new developments for the controlled fabrication of monodisperse emulsions using microfluidics. We use glass capillary devices to generate single, double, and higher order emulsions with exceptional precision. These emulsions can serve as ideal templates for generating well-defined particles and functional vesicles. Polydimethylsiloxane microfluidic devices are also used to generate picoliter-scale water-in-oil emulsions at rates as high as 10 000 drops per second. These emulsions have great potential as individual microvessels in high-throughput screening applications, where each drop serves to encapsulate single cells, genes, or reactants.

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