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Familial Spontaneous Pneumothorax and HLA Antigens

1980; Elsevier BV; Volume: 78; Issue: 2 Linguagem: Inglês

10.1378/chest.78.2.264

1931-3543

Isabella K. Sharpe, Muzaffar Ahmad, William E. Braun,

Neonatal Respiratory Health Research

Twenty-three members of a family in which six persons had repeated spontaneous pneumothorces were studied for physical, chemical and genetic markers of this disease. A relationship between the HLA haplotype A2, B40, the alpha 1, antitrypsin phenotype M1 M2 and the occurrence of spontaneous pneumothorax was suggested in this family.