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The effect of captopril on cutaneous blood flow in patients with primary Raynaud's phenomenon

1987; Oxford University Press; Volume: 117; Issue: 6 Linguagem: Inglês

10.1111/j.1365-2133.1987.tb07356.x

1365-2133

M.H.A. RUSTIN, N. E. Almond, Julie Beacham, Randall Brooks, D. P. Jones, E D Cooke, Pauline M. Dowd,

Urticaria and Related Conditions

Fifteen patients with primary Raynaud's phenomenon received captopril 25 mg or placebo, three times daily for 6 weeks, in a randomized double-blind cross-over study. Compared with placebo, captopril produced a significant improvement in cutaneous blood flow but did not alter the frequency or severity of attacks of Raynaud's phenomenon.