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BIBTEX RIS

Effects of immunosuppression on immune response to pneumococcal vaccine in inflammatory bowel disease: A prospective study*

2011; Oxford University Press; Volume: 18; Issue: 6 Linguagem: Inglês

10.1002/ibd.21800

ISSN

1536-4844

Autores

Gionata Fiorino, Laurent Peyrin‐Biroulet, Patrizia Naccarato, Hajnalka Szabó, Orsola Sociale, Stefania Vetrano, Walter Fries, Alessandro Montanelli, Alessandro Repici, Alberto Malesci, Silvio Danese,

Tópico(s)

Gastrointestinal Bleeding Diagnosis and Treatment

Resumo

BackgroundSince immunomodulators and antitumor necrosis factor (TNF) agents are increasingly used to treat inflammatory bowel disease (IBD), it is recommended to administer antipneumococcal vaccination to prevent opportunistic pneumonia. There is some evidence that concomitant immunosuppression may impair the immune response to vaccination. We aimed to evaluate the response rates to pneumococcal vaccination in four different treatment groups (mesalamine, azathioprine, infliximab, infliximab plus azathioprine).

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