Voltar
Artigo
BIBTEX RIS

Solid phase peptide synthesis after 25 years: The design and synthesis of antagonists of glucagon

1988; Wiley; Volume: 19; Issue: 1 Linguagem: Inglês

10.1002/masy.19880190104

ISSN

0258-0322

Autores

R. B. Merrifield,

Tópico(s)

Biochemical and Structural Characterization

Resumo

Makromolekulare Chemie. Macromolecular SymposiaVolume 19, Issue 1 p. 31-67 Article Solid phase peptide synthesis after 25 years: The design and synthesis of antagonists of glucagon R. B. Merrifield, R. B. Merrifield The Rockefeller University, New York, N.Y. 10021, USASearch for more papers by this author R. B. Merrifield, R. B. Merrifield The Rockefeller University, New York, N.Y. 10021, USASearch for more papers by this author First published: June 1988 https://doi.org/10.1002/masy.19880190104Citations: 15AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 R. B. Merrifield, Federation Proc. 21, 412 (1962). 2 R. B. Merrifield and D. W. Woolley, J. Am. Chem. Soc. 78, 4646 (1956) 3 R. B. Merrifield and D. W. Woolley, Federation Proc. 17, 275 (1958). 4 R. B. Merrifield, J. Am. Chem. Soc. 85, 2149 (1963). 5 R. B. Merrifield, Biochemistry 3, 1385 (1964). 6 A. R. Mitchell, S. B. H. Kent, B. W. Erickson and R. B. Merrifield, Tetrahedron Lett., 3795 (1976) 7 A. R. Mitchell, B. W. Erickson, M. N. Ryabtsev, R. H. Hodges and R. B. Merrifield, J. Am. Chem. Soc. 98, 7357 (1976). 8 H. Hagenmaier and H. Frank, Hoppe-Seyler's Z. Physiol. Chem. 353, 1973 (1972). 9 J. P. Tam, W. F. Heath and R. B. Merrifield J. Am. Chem. Soc. 105, 6442 (1983). 10 B. W. Erickson and R. B. Merrifield, in The Proteins, Vol II, 3rd Ed, ( H. Neurath and R. L. Hill, eds) Academic Press, New York, 1976, p. 367. 11 G. Barany and R. B. Merrifield, in The Peptides, Vol 2, ( E. Gross and J. Meienhofer, eds), Academic Press, N.Y., 1979, p. 1. 12 R. B. Merrifield and V. Littau, in Peptides 1968, (E. Bricas ed) North Holland Co., Amsterdam, 1968, p. 179. 13 K. K. Bhargava, V. K. Sarin, N. L. Trang, A. Cerami and R. B. Merrifield, J. Am. Chem. Soc. 105, 3247 (1983). 14 D. H. Live and S.B.H. Kent, in Peptides: Structure and Function, (V. Hruby and D. Rich, eds), Pierce Chem. Co., Rockford, Ill., 1983, p 65. 15 S. L. Regen, J. Am. Chem. Soc. 96, 5275 (1974). 16 R. B. Merrifield, British Polymer Journal 16, 173 (1984). 17 B. Hetnarski and R. B. Merrifield, 10th Amer. Peptide Symp., Washington University, St. Louis, 1987, Abstract P-40. 18 S. Pickup, F. D. Blum, W. T. Ford and M. Periyasamy, J. Am. Chem. Soc. 108, 3987 (1986). 19 V. K. Sarin, S.B.H. Kent, J. P. Tam and R. B. Merrifield, Anal. Biochem. 117, 147 (1981). 20 B. F. Gisin, Anal. Chim. Acta 58, 248 (1972). 21 R. B. Merrifield, L. D. Vizioli and H. G. Boman, Biochemistry 21, 5020 (1982). 22 V. K. Sarin, S.B.H. Kent, A. R. Mitchell and R. B. Merrifield, J. Am. Chem. Soc. 106, 7845 (1984). 23 V. K. Sarin, S.B.H. Kent and R. B. Merrifield, J. Am. Chem. Soc. 102, 5463 (1980). 24 R. C. Sheppard, in Peptides 1971 (H. Nesvadba, ed) North Holland Publ., Amsterdam, 1973, p 111. 25 R. B. Merrifield, J. M. Stewart and N. Jernberg, Anal. Chem. 38, 1905 (1966). 26 J. B. Taylor and H. E. Swaisgood, Biochem. Biophys. Acta 284, 268 (1972). 27 H. M. Geysen, R. H. Meloen and S. J. Barteling, Proc. Natl. Sci. USA 81, 3998 (1984) 28 R. A. Houghton, Proc. Natl. Acad. Sci. USA 82, 5131 (1985) 29 R. H. Unger, Diabetes 25, 136 (1976). 30 D. J. Koerker, W. Ruch, E. Ehedeckel, J. Palmer, C. J. Goodner, J. Ensinck and C. C. Gale, Science 184, 482 (1974) 31 E. Schroder, E., in “Peptides” (H.C. Beyerman, A. van de Linde and N. Maassen van den Brink, eds), North-Holland Pub. Co., Amsterdam, 1967, p 245. 32 E. Wünsch, presented at the 8th European Peptide Symposium, Noordwijke, Holland, Sept. 1966. 33 W. W. Bromer, L. Sinn and O. K. Behrens, J. Am. Chem. Soc. 79, 2807 (1957). 34 E. Wünsch and G. Wendelberger, Chem. Ber. 101, 3659 (1968). 35 Protein Synthesis Group, Shanghai Institute of Biochemistry, Sci. Sin. 18, 745 (1975) 36 R. B. Merrifield, G. Barany, W. L. Cosand, M. Engelhard and S. Mojsov, in Peptides (M. Goodman and J. Meienhofer, eds) Wiley, N.Y., 1977, p 488. 37 S. Mojsov and Merrifield, R. B. Biochemistry 20, 2950– 2956 (1981). 38 S. Mojsov and R. B. Merrifield, Eur. J. Biochem. 145, 601 (1984). 39 R. B. Merrifield and S. Mojsov, in Handbook of Experimental Pharmacology, Vol 66/I, Chap. 2, (P.J. Lefèbvre, ed), Springer, Berlin, 1983, p 23. 40 P. Y. Chou and G. D. Fasman, Biochemistry 14, 2536 (1975) 41 D. Andreu and R. B. Merrifield, in Peptides: Structure and Function (C.M. Deber, V.J. Hruby and K.D. Kopple, eds), Pierce Chem. Co., Rockford, IL, 1985, p 595. 42 Lin, M. C., Wright, D. E., Hruby, V. J. and Rodbell, M., Biochemistry 14, 1559 (1975). 43 R. B. Merrifield, C. Unson, E. M. Gurzenda and Andreu, D., in Peptides 1986, (D. Theodoropoulos, ed), Walter de Gruyter and Co., Berlin, 1987, p 517. 44 J. M. Stewart, E. J. York, R. L. Baldwin and K. R. Shoemaker, in Peptides 1986, (D. Theodoropoulos, ed), Walter de Gruyter and Co., Berlin, 1987, p 287. 45 M. Rosenblatt, G. H. Mahaffey and J. T. Potts, in Peptides: Structure and Function, (M. Goodman and J. Meienhofer, eds) Wiley, New York, 1977, p 581. 46 D. F. Veber, F. W. Holly, R. F. Nutt, S. J. Bergstrand, S. F. Brady, R. Hirschmann, M. S. Glitzer and R. Saperstein, Nature 280, 512 (1979). 47 P. Y. Chou, and G. D. Fasman, Advances in Enzymology 2, 45 (1978). 48 J. Murphy, W-j. Zhang, W. Macaulay, G. Fasman and R. B. Merrifield, J. Biol. Chem. 1987, in press. 49 Y. Salomon, C. Londos and M. Rodbell, Anal. Biochem. 58, 541 (1974). 50 D. E. Wright and M. Rodbell, J. Biol. Chem. 254, 268 (1979). 51 D. Andreu and R. B. Merrifield, Eur. J. Biochem. 164, 585 (1987). 52 D. Andreu and B. Merrifield, in Peptides: Structure and Function, (C.M. Deber, V.J. Hruby and K.D. Kopple, eds), Pierce Chem. Co., Rockford, IL, 1985, p 595. 53 H. O. Schild, Br. J. Pharmacol. 2, 189 (1947). 54 O. Arunlakshana and H. O. Schild, Br. J. Pharmacol. 14, 48 (1959). 55 G.-s. Lu, S. Mojsov and R. B. Merrifield, Int. J. Pept. Protein Res. 29, 545 (1987). 56 R. B. Merrifield, C. Unson, E. M. Gurzenda and D. Andreu, in Peptides 1986, de Gruyter, Berlin, 1987, p 517. 57 C. G. Unson, D. Andreu, E. M. Gurzenda and R. B. Merrifield, Proc. Natl. Acad. Sci. USA 84, 4083 (1987). 58 M. Rosenblatt, G. H. Mahaffey and J. T. Potts, in Peptides: Structure and Function, (M. Goodman and J. Meienhofer, eds) Wiley, New York, 1977, p 581. 59 J. Sueiras-Diaz, V. A. Lance, W. A. Murphy and D. H. Coy, J. Med. Chem. 27, 310 (1984). 60 J. L. Krstenansky, B. Gysin, D. Trivedi and V. J. Hruby, in Peptides: Structure and Function, (C.M. Deber, V.J. Hruby and K.D. Kopple, eds), Pierce Chemical Co., Rockford, IL, 1985, p 591. 61 R. L. McKee, J. T. Pelton, D. Trivedi, D. G. Johnson, D. H. Coy, J. Sueiras-Diaz and V. J. Hruby, Biochemistry 25, 1650 (1986). 62 K. R. Shoemaker, P. S. Kim, D. N. Brems, S. Marquess, E. J. York, I. M. Chaiken, J. M. Stewart and R. L. Baldwin, Proc. Natl. Acad. Sci. USA 82, 2349 (1985). 63 K. R. Shoemaker, P. S. Kim, E. J. York, J. M. Stewart and R. L. Baldwin, Nature 326, 563 (1987). 64 C. G. Unson and R. B. Merrifield, unpublished data. 65 A. P. Korn and F.P Ottensmeyer, J. Theor. Biol. 105, 403 (1983). 66 H. Kofod, Regulatory Peptides 15, 229 (1986). 67 H. Kofod, D. Andreu, P. Thams, C. J. Hedeskov, R. B. Merrifield, C. J. Hedeskov, B. Hansen, Å. Lernmark and T. Nielsen, Amer. J. Physiol. 1987, in press. 68 M.J.O. Wakelam, G. S. Murphy, V. J. Hruby and M. D. Houslay, Nature (London) 323, 68 (1986). 69 C. G. Unson, E. M. Gurzenda and R. B. Merrifield, (1987) unpublished data. Citing Literature Volume19, Issue1June 1988Pages 31-67 ReferencesRelatedInformation

Referência(s)