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Glia and Muscle Sculpt Neuromuscular Arbors by Engulfing Destabilized Synaptic Boutons and Shed Presynaptic Debris

2009; Public Library of Science; Volume: 7; Issue: 8 Linguagem: Inglês

10.1371/journal.pbio.1000184

1545-7885

Yuly Fuentes-Medel, Mary A. Logan, James Ashley, Bulent Ataman, Vivian Budnik, Marc Freeman,

Retinal Development and Disorders

As synapses grow at the Drosophila neuromuscular junction, they shed membrane material in an activity-dependent manner. Glia and postsynaptic muscle cells are required to engulf this debris to ensure new synaptic growth.