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PFD: a database for the investigation of protein folding kinetics and stability

2004; Oxford University Press; Volume: 33; Issue: Database issue Linguagem: Inglês

10.1093/nar/gki016

1362-4962

Kate F. Fulton, Glyn L. Devlin, Rachel A. Jodun, Linda Silvestri, Stephen Bottomley, Alan R. Fersht, Ashley M. Buckle,

Microbial Metabolic Engineering and Bioproduction

We have developed a new database that collects all protein folding data into a single, easily accessible public resource. The Protein Folding Database (PFD) contains annotated structural, methodological, kinetic and thermodynamic data for more than 50 proteins, from 39 families. A user-friendly web interface has been developed that allows powerful searching, browsing and information retrieval, whilst providing links to other protein databases. The database structure allows visualization of folding data in a useful and novel way, with a long-term aim of facilitating data mining and bioinformatics approaches. PFD can be accessed freely at http://pfd.med.monash.edu.au .