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Silica coating improves the efficacy of Pd nanosheets for photothermal therapy of cancer cells using near infrared laser

2011; Royal Society of Chemistry; Volume: 47; Issue: 13 Linguagem: Inglês

10.1039/c1cc10451a

1364-548X

Shaoheng Tang, Xiaoqing Huang, Nanfeng Zheng,

Nanoparticle-Based Drug Delivery

Thickness does matter! The ultrathin nature of 1.8 nm-thick Pd nanosheets prevents them entering cells effectively. A 13-times enhancement in the cells' uptake of the Pd nanosheets has now been achieved by silica coating together with surface functionalization, therefore significantly improving their NIR photothermal cell-killing efficacy.