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BIBTEX RIS

Poor Clinical Sensitivity of Rapid Antigen Test for Influenza A Pandemic (H1N1) 2009 Virus

2009; Centers for Disease Control and Prevention; Volume: 15; Issue: 10 Linguagem: Inglês

10.3201/eid1510.091186

ISSN

1080-6059

Autores

Jan Felix Drexler, Angelika Helmer, Heike Kirberg, Ulrike Reber, Marcus Panning, Marcel A. Müller, Katja Höfling, B. Matz, Christian Drosten, Anna Maria Eis‐Hübinger,

Tópico(s)

Viral gastroenteritis research and epidemiology

Resumo

Influenza A pandemic (H1N1) 2009 virus RNA was detected by reverse transcription-PCR in 144 clinical samples from Bonn, Germany. A common rapid antigen-based test detected the virus in only 11.1% of these samples. The paramount feature of rapid test-positive samples was high virus concentration. Antigen-based rapid tests appear unsuitable for virologic diagnostics in the current pandemic.

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