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Reversed halo sign in lymphomatoid granulomatosis

2007; Wiley; Volume: 80; Issue: 956 Linguagem: Inglês

10.1259/bjr/46361210

1748-880X

Rachel Benamore, G L Weisbrod, Dong-Yeon Hwang, Denis Bailey, A.F. Pierre, Neil M. Lazar, Nimrod Maimon,

Autoimmune and Inflammatory Disorders

Lymphomatoid granulomatosis is a rare lymphoproliferative disorder which affects extranodal sites, most commonly lung. Radiologically, it typically presents with multiple nodular opacities that may wax and wane. The reversed halo sign has previously been reported in cryptogenic organizing pneumonia and more recently in South American blastomycosis. We describe a case of histologically proven lymphomatoid granulomatosis in a patient who presented initially with the more typical nodular opacities, which subsequently progressed into the reversed halo sign. To the best of our knowledge, this association has not been previously described.