Lipase catalysed Michael addition of secondary amines to acrylonitrile
2004; Royal Society of Chemistry; Issue: 15 Linguagem: Inglês
10.1039/b402244k
ISSN1364-548X
AutoresOliver Torre, Ignacio Alfonso, Vicente Gotor,
Tópico(s)Microbial Metabolic Engineering and Bioproduction
ResumoA new enzymatic process is described. Different preparations of lipase B from Candida antarctica are able to catalyse Michael-type addition of secondary amines to acrylonitrile. This new reaction widens the applicability of these biocatalysts in organic synthesis.
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