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Optical Properties of Wounds: Diabetic Versus Healthy Tissue

2006; Institute of Electrical and Electronics Engineers; Volume: 53; Issue: 6 Linguagem: Inglês

10.1109/tbme.2006.873541

1558-2531

Elisabeth S. Papazoglou, Michael S. Weingarten, Leonid Zubkov, Linda Zhu, S. Tyagi, Kambiz Pourrezaei,

Photoacoustic and Ultrasonic Imaging

Diffuse photon density wave (DPDW) methodology at Near Infrared frequencies has been used to calculate absorption and scattering from wounds of healthy and diabetic rats. The diffusion equation for semi-infinite media is being used for calculating the absorption and scattering coefficients based on measurements of phase and amplitude with a frequency domain device. Differences observed during the course of healing in the two populations can be correlated to the delayed healing observed in diabetics. These results are encouraging and further work will focus on the implementation of this device to the clinical setting as a monitoring tool in chronic diabetic wounds.